RecruitingNot ApplicableNCT06800469

Gut Microbiota Analysis in Patients Undergoing Duodencephalopancreasectomy for Pancreatic Cancer

Gut Microbiota Analysis in Patients Undergoing Duodencephalopancreasectomy for Pancreatic Cancer (MIcRobiome Analysis in Patients UnderGoing PancrEatico-duodenectomy for Pancreatic Cancer MIRAGE Study)


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

30 participants

Start Date

Jul 11, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Pancreatic head cancer represents one of the most frequent malignancies with an incidence of about 13500 new cases each year. The primary objective of the study is to test whether there are bacterial species associated with increased risk of complications in patients with peri-ampullary neoplasia undergoing DCP.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥18 years
  • Diagnosis of resectable pancreatic adenocarcinoma with indication for "upfront" surgical treatment
  • ASA (American Society of Anesthesiology) score \< 4
  • Obtaining informed consent

Exclusion Criteria1

  • \- Pregnant or lactating women

Interventions

DIAGNOSTIC_TESTMicrobiota analysis

Upon acquisition of informed consent, fecal, digiunal mucosa, biliary and pancreatic fluid samples will be collected for microbiota analysis


Locations(1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, BO, Italy

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NCT06800469


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