RecruitingNCT06800586

Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects

Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

300 participants

Start Date

Sep 15, 2025

Study Type

OBSERVATIONAL

Conditions

Leukemia Lung Cancer (NSCLC)COPD

Summary

This study aims to examine the exposure to atmospheric pollutants in a group of non-smoking patients suffering from lung cancer, chronic obstructive pulmonary disease (COPD), and leukemia. The exposure to atmospheric pollutants will be assessed simultaneously in a group of healthy volunteers. The ultimate goal of the study is to enhance the understanding of the mechanisms by which atmospheric pollutants act, in order to develop new tools that can help halt or at least delay the development of diseases associated with pollution.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking for new biological markers in the blood and urine that could help detect lung disease and cancer caused by air pollution — particularly in people with COPD who have never smoked. **You may be eligible if...** - You are 18 or older - You have a diagnosis of COPD (a chronic lung disease) AND have never been a significant smoker, OR - You are a healthy volunteer with no lung disease or smoking history **You may NOT be eligible if...** - You are a current or past significant smoker (defined as more than 100 cigarettes in your lifetime) - You have another active respiratory illness (for the healthy volunteer group) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Locations(3)

Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, Italy

Respiratory and Critical Care Unit, IRCCS Azienda Ospedaliera-Universitaria di Bologna

Bologna, Bologna, Italy

Ematology Unit, Azienda Ospedaliero-Universitaria, Policlinico Riuniti di Foggia

Foggia, Foggia, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06800586

Related Trials

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

NCT052379863 locations

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

NCT071192294 locations

Digital Tool for Improved Self-management of COPD

NCT075730981 location

The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease

NCT067958151 location

Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

NCT058965791 location