Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery
Application of Gaseous Ozone in the Surgical Extraction of Impacted Mandibular Third Molars: Impact on the Incidence of Postoperative Complications and Healing Processes
Jelena Krunic
20 participants
Dec 1, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life. The main questions it aims to answer are: * Does ozone reduce incidence of postoperative compliactions such as pain, swelling or reduced mouth opening after impacted mandibular third molar surgery? * Does ozone improve wound healing after impacted mandibular third molar surgery? * Does ozone have positive effect on quality of life after impacted mandibular third molar surgery? Participants will: * Receive ozone after impacted mandibular third molar surgery. * Visit the clinic 1st, 3rd, and 7th days after the intervention for checkups and tests. * Keep a diary of their symptoms.
Eligibility
Inclusion Criteria3
- Patients over 18 years
- Patients with bilaterally impacted mandibular third molars classified as impaction index II B
- Patients in good general health (based on the ASA classification as ASA I and ASA II).
Exclusion Criteria4
- Contraindications for ozone application (pregnancy, hyperthyroidism, favism, anemia, myasthenia, bleeding disorders, alcohol intoxication, myocardial infarction, pacemaker, allergy to ozone)
- Patients who have used corticosteroid and antibiotic therapy in the last three months prior to inclusion in the study
- Patients with signs of local inflammation in the oral cavity
- Female patients during pregnancy and breastfeeding.
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Interventions
In Ozone group, ozone will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar, according to the manufacturer's recommendation for wound treatment following tooth extraction.
In the control group, a sham ozone therapy will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar .
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06802354