RecruitingNCT06804265

Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections

Molecular Biology (Multiplex PCR) in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections (PJI)


Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Enrollment

100 participants

Start Date

Jan 7, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to measure the diagnostic accuracy of the Multiplex PCR technique in identifying pathogens during the diagnostic stage of resolving pre-implantation infection, in the context of treatment according to two-stage protocol for PJIs. This evaluation will be conducted by comparing the results obtained by Multiplex PCR with those derived from standard culture examination.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Diagnosis of periprosthetic infection of hip, knee, shoulder on primary or already revised implant.
  • treatment of infection with two-stage protocol.
  • Obtaining informed consent
  • Age ≥18 years

Exclusion Criteria1

  • Isolates obtained during explantation not included in MULTIPLEX PCR panel

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Locations(1)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy

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NCT06804265


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