Urine Methylation Markers in UTUC
Urine-based Methylation Markers in the Diagnosis and Surveillance of Upper Tract Urothelial Carcinoma
Duke University
50 participants
May 7, 2025
INTERVENTIONAL
Conditions
Summary
This is a research study to measure DNA markers in the urine of patients with upper tract urothelial cancer (UTUC) before surgery and during follow-up visits. Identifying these DNA markers could improve diagnosis before surgery, help assess risk, and predict early recurrence of the cancer. Urine samples will be de-identified and sent to Pangea Laboratory LLC for analysis. The results of this test will be compared to the traditional tests in upper tract urothelial cancer, such as cells in the urine and tissue biopsy.
Eligibility
Inclusion Criteria2
- >=18 years
- Primary UTUC
Exclusion Criteria1
- Patients who do not understand and/or are unwilling to sign a written informed consent
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Interventions
Urine methylation biomarker test
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06805630