Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
Correlation Study Between Clinical, Neurophysiological, and Neuroradiological Biomarkers and Rehabilitation Outcomes to Predict Functional Recovery After Stroke and Personalize Treatment.
IRCCS San Raffaele Roma
300 participants
Jun 15, 2020
OBSERVATIONAL
Conditions
Summary
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability post-stroke. The goal is to construct an integrated individual biomarker algorithm with a high predictive value for outcomes.
Eligibility
Inclusion Criteria5
- First stroke in the middle cerebral artery territory.
- Ischemic or hemorrhagic stroke (7-30 days post-acute event).
- Upper limb plegia or paresis.
- Both genders, aged >18 years.
- Ability to provide informed consent by the patient or caregiver/responsible relative.
Exclusion Criteria6
- Previous stroke.
- Stroke in territories other than the middle cerebral artery.
- Inability to provide informed consent.
- Contraindications to TMS or MRI.
- History of cancer in the past two years.
- Presence of other neurological conditions interfering with biomarkers
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06805929