RecruitingPhase 2Phase 3NCT06807021

Post-Operative Use of FS2 to Mitigate Scarring in Burn Patients

Post-operative Topical Administration of Fibrosis Inhibiting Compound FS2 in a Double- Blind, Randomized, Vehicle-controlled Study Evaluating the Safety and Mitigation of Cutaneous Scarring in Skin Graft and Donor Sites in Burn Patients


Sponsor

Birch BioMed Inc

Enrollment

70 participants

Start Date

May 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to see how an ingredient called kynurenic acid (which we named "FS2") affects scar formation in people with burn injuries that need skin graft surgery. A cream with FS2 will be used on both the area where the skin graft was placed and the area where the skin was taken (donor site). The cream will be applied after the skin has healed. This study will help us understand if FS2 is safe and effective for mitigating skin scar formation in burn patients.


Eligibility

Min Age: 12 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called IP1 control cream (Vehicle base) and a drug called IP2 - 0.5% w/w FS2 for people with burn wound and burn scar. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 12 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIP1 control cream (Vehicle base)

Without FS2

DRUGIP2 - 0.5% w/w FS2

FS2 in pharmaceutical compounding base


Locations(2)

University of Alberta, Division of Plastic Surgery

Edmonton, Alberta, Canada

Centre for Burn Research - Hamilton Health Sciences

Hamilton, Ontario, Canada

View Full Details on ClinicalTrials.gov

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NCT06807021


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