RecruitingNot ApplicableNCT06807502

Evaluation of Circulating Tumor Cells (CTC) Relevance in Breast Cancer Follow-up Using the ScreenCell Device


Sponsor

ScreenCell

Enrollment

93 participants

Start Date

Feb 24, 2025

Study Type

INTERVENTIONAL

Summary

Liquid biopsy is a noninvasive method for detecting and quantifying circulating tumor cells (CTCs). Thanks to ScreenCell technology, this study aims to evaluate the evolution of the number of CTCs during breast cancer follow-up. The identification and characterization of CTCs would make it possible to obtain information on the stage and molecular characteristics of cancer during follow-up


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria9

  • For all participants :
  • Age greater than or equal to 18 years
  • For participants with metastatic breast cancer:
  • \- Patient observed with metastatic breast cancer from the outset or metastatic fall from previously treated breast cancer with change of therapeutic line at the time of inclusion.
  • For participants with non-metastatic invasive breast cancer:
  • \- Patient observed with non-metastatic infiltrative breast cancer who had not received any treatment at the time of inclusion (naïve to any treatment)
  • For healthy volunteers:
  • Participant free of any cancer at the time of inclusion, confirmed using a mammogram whose results must be satisfactory, done at the latest one year before inclusion
  • Participant with no history of cancer

Exclusion Criteria10

  • For all participants:
  • Age less than 18 years old
  • Refusal to participate or withdrawal of consent
  • Pregnant and/or breastfeeding women
  • Discovery of a cancerous pathology (other than breast cancer for patients) during participant follow-up.
  • For participants with breast cancer:
  • \- Absence of CTC during screening
  • For healthy volunteers:
  • History of cancer
  • Detection of CTC (positive profile) during screening

Interventions

DEVICEThe DM/DIV ScreenCell is the experimental product studied during this research

The product is not used directly on the subject, but on a blood sample taken from the participant.


Locations(1)

CMC Ambroise Paré Hartmann

Neuilly-sur-Seine, France

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NCT06807502