RecruitingNot ApplicableNCT06808945

Preoperative Prehabilitation in Patients Planned for Liver Transplantation

Preoperative PREhabilitation in Patients Planned for LIVER Transplantation (PRELIVERT)


Sponsor

Erasmus Medical Center

Enrollment

60 participants

Start Date

Oct 2, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to determine the feasibility and effectiveness of a home-based multimodal prehabilitation program in patients anticipated to be waitlisted for LT. Patients will participate in an eight week prehabilitation program consisting of physical exercise, nutritional support, smoking cessation and psychological counselling.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥18 years,
  • Anticipated waitlisting for LT,
  • Speaks the Dutch language,
  • Understands the purpose of the study and has given written informed consent.

Exclusion Criteria8

  • Experienced a major adverse cardiovascular event in the past six months,
  • Experienced a cerebrovascular incident in the past six months,
  • Medical history of an uncontrolled heart rhythm disorder,
  • Hepatic encephalopathy grade 3 or 4,
  • Acute liver failure,
  • Acute-on-chronic liver failure,
  • Hospitalization at start of the study.
  • Non-treated esophageal varices (i.e., no previous variceal eradication endoscopy or adequately dosed NSBB)

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Interventions

OTHERPrehabilitation program

Participants will be subjected to an eight week home-based multimodal prehabilitaiton program. The program consists of an exercise program, nutritional support, smoking cessation and psychological counselling.


Locations(1)

Erasmus Medical Center

Rotterdam, Netherlands

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NCT06808945


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