The Ventilation During In-hospital Cardiac Arrest Study
The Ventilation During In-Hospital Cardiac Arrest (VENT-IHCA) Study
University of Aarhus
900 participants
Feb 1, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult patients. The main questions it aims to answer are: What ventilation volume during CPR is associated with the highest chance of return of spontaneous circulation (ROSC)? What ventilation rate during CPR is associated with the highest chance of ROSC? Researchers will compare different levels of ventilation rates and volumes that are blindly measured during CPR to see how the observed rates and volumes are associated with survival outcomes and complications.
Eligibility
Inclusion Criteria3
- In-hospital cardiac arrest
- Age ≥ 18 years
- \>1minute of recorded ventilation data
Exclusion Criteria2
- Documented do-not-attempt cardiopulmonary resuscitation order
- Invasive mechanical circulatory support at the time of the cardiac arrest
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Interventions
The primary exposures of interest are the observed ventilation rate, tidal volume and minute ventilation during cardiopulmonary resuscitation. Ventilation data are obtained by inspiratory and expiratory air flow measurements using the EOlife (Archeon, Besançon, France) to which healthcare providers are blinded.
Locations(11)
View Full Details on ClinicalTrials.gov
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NCT06809309