RecruitingNCT06810960

A Postmarketing Study of Lecanemab in South Korean Participants With Alzheimer's Disease

A 6-Year Postmarketing Safety and Clinical Outcome Study of Lecanemab in the Treatment of Alzheimer's Disease Using Real-World Data From South Korean Patients Enrolled Into the South Korean JOint RegistrY for ALZheimer's Treatment and Diagnostics (JOY-ALZ) Registry


Sponsor

Eisai Korea Inc.

Enrollment

3,000 participants

Start Date

Feb 24, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The primary purpose of this study is to evaluate safety of lecanemab in the real-world clinical setting as reported by events of amyloid-related imaging abnormalities (ARIA)-edema (ARIA-E), ARIA-hemosiderin deposition (ARIA-H), symptomatic ARIA-E, symptomatic ARIA-H, and intracerebral hemorrhage (ICH) greater-than 1 centimeter (cm) in participants treated with lecanemab.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • years or older at consent
  • Prior to JOY-ALZ enrollment, the treating physician confirms that the participant is suitable for lecanemab treatment, as per the approved indications in South Korea
  • Has an identified study partner who provides separate written informed consent
  • Provides written informed consent for the use of medical information to be shared with Eisai Korea Inc.

Exclusion Criteria2

  • Currently participating in an interventional clinical study
  • Has contraindications for lecanemab according to the approved prescribing information in South Korea

Interventions

OTHERNo Intervention

This is a non-interventional study.


Locations(1)

Eisai Trial Site #1

Nutley, New Jersey, United States

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NCT06810960


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