Alzheimer s Disease Clinical Trials

59 recruiting

Frequently Asked Questions

Common questions about Alzheimer s Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting

Lombard Cohort of Brain Health Services

Alzheimer s DiseaseSubjective Cognitive Decline (SCD)Functional Cognitive Disorder+1 more
University of Milano Bicocca1,000 enrolled5 locationsNCT07457138
Recruiting

Precision Medicine and Neurodegenerative Diseases: Advanced Systems for the Diagnosis and Treatment of Parkinson's Disease and Alzheimer's Disease.

Diabete Type 2PARKINSON DISEASE (Disorder)Alzheimer s Disease
Neuromed IRCCS500 enrolled1 locationNCT07467460
Recruiting
Phase 1

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

Alzheimer s Disease
Hoffmann-La Roche50 enrolled2 locationsNCT07234942
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

Alzheimer s Disease
Bristol-Myers Squibb586 enrolled121 locationsNCT06976203
Recruiting
Phase 1

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentAlzheimer s Disease
University of California, San Diego60 enrolled1 locationNCT06548191
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Alzheimer s Disease
Bristol-Myers Squibb586 enrolled111 locationsNCT06976216
Recruiting
Phase 1

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Alzheimer s Disease
Alnylam Pharmaceuticals50 enrolled6 locationsNCT07214727
Recruiting
Phase 1

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting

Assessment of Informal Support Provided by Caregivers at Different Stages of Alzheimer's Disease

Elderly (People Aged 65 or More)Alzheimer s DiseaseNeurocognition
Hospices Civils de Lyon312 enrolled1 locationNCT07409506
Recruiting

VR Pupillometry in Cognitive Impairment

DementiaMajor Depressive Disorder (MDD)Mild Cognitive Impairment+1 more
Max-Planck-Institute of Psychiatry140 enrolled1 locationNCT07402356
Recruiting

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Memory DisordersMild Cognitive ImpairmentMemory Impairment+3 more
GAP Innovations, PBC1,200 enrolled25 locationsNCT06584357
Recruiting

Retinal Imaging in Neurodegenerative Disease

Traumatic Brain InjuryHuntington DiseaseNeuro-Degenerative Disease+12 more
Duke University2,000 enrolled1 locationNCT03233646
Recruiting
Phase 2

Open-label Extension Study in Participants With Early Alzheimer's Disease

Alzheimer s Disease
GlaxoSmithKline220 enrolled33 locationsNCT07105709
Recruiting
Phase 1Phase 2

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

Multiple SclerosisAlzheimer s Disease
Brigham and Women's Hospital250 enrolled1 locationNCT02649985
Recruiting

A Post Marketing Study in Participants With Early Alzheimer's Disease Treated With Lecanemab

Alzheimer s Disease
Eisai Co., Ltd.5,000 enrolled3 locationsNCT06322667
Recruiting
Not Applicable

Evaluation of a Plasma Marker (p-Tau217) for the Biological Diagnosis of Alzheimer's Disease, and Comparison With CSF Markers

BiomarkersNon-invasive DiagnosisAlzheimer s Disease+1 more
Centre Hospitalier Universitaire, Amiens40 enrolled1 locationNCT07071649
Recruiting
Not Applicable

Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.

ObesityMetabolic SyndromeInflammation+5 more
University of Seville8 enrolled1 locationNCT07361887
Recruiting
Not Applicable

Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment of Alzheimer's Disease

Alzheimer s Disease
Fujian Medical University Union Hospital66 enrolled1 locationNCT07324161
Recruiting
Not Applicable

Effect of Cervical Lymphaticovenous and Lymph Node-to-Vein Anastomosis in Patients With Intracranial Lymphatic Circulation Disorder

Alzheimer s DiseaseIntracranial Lymphatic Circulation Disorder
Hong Joonpio114 enrolled1 locationNCT07328386