RecruitingPhase 4NCT06813963

Minoxidil for Treating White Hair: A Randomized Controlled Trial

A Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Minoxidil in the Repigmentation of White Hair in Adults


Sponsor

Southern Medical University, China

Enrollment

100 participants

Start Date

Feb 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate whether topical Minoxidil can restore hair pigmentation in individuals with non-pathological graying hair. The study population includes male and female participants aged \[18to65\] who have non-pathological graying of hair, meaning their graying is not due to any underlying medical conditions. The main questions it aims to answer are: Does topical Minoxidil improve hair pigmentation in individuals with non-pathological graying hair? What medical problems do participants have when topical use minoxidil? Researchers will compare participants receiving topical Minoxidil to those receiving a placebo to determine whether Minoxidil has a significant effect on restoring hair pigmentation. Participants will: Topical use minoxidil or a placebo twice a day for 12 months Visit the clinic once every months for checkups and tests Report any adverse effects or changes in hair characteristics throughout the study.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • The patients included in the study were those with a visible gray hair grading score of 2 or higher at screening and baseline visits, with depigmented hair shafts observable under dermoscopy.

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Interventions

DRUGTopical Minoxidil(5%) to the scalp.

The patient will apply 5% Minoxidil topical solution to the scalp twice daily, with 7 sprays (approximately 1 mL) per application, for a duration of 12 months.

DRUGPlacebo

The patient will apply placebo to the scalp twice daily, with 7 sprays (approximately 1 mL) per application, for a duration of 12 months.


Locations(2)

Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China

The First People's Hospital of Zhaoqing

Zhaoqing, Guangdong, China

View Full Details on ClinicalTrials.gov

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NCT06813963