RecruitingPhase 3NCT06819826

A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of SC0062 Capsule in Patients with IgA Nephropathy and Proteinuria (SUCCESS-1)


Sponsor

Biocity Biopharmaceutics Co., Ltd.

Enrollment

360 participants

Start Date

Feb 14, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a multicenter, randomized, double-blind, placebo-controlled Phase III study to evaluate the efficacy and safety of SC0062 capsule compared to placebo in patients with IgA nephropathy in the presence of proteinuria. The participants must have a high risk of disease progression, despite of stable use of the maximum tolerated labelled or optimized dose of RAASi and/or SGLT2i for at least 12 weeks prior to randomization.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo matched to SC0062 and a drug called SC0062 strength 10mg for people with iga nephropathy (igan). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGSC0062 strength 10mg

Subjects will take 20 mg once daily for 108 weeks during the treatment period.

DRUGPlacebo matched to SC0062

Subjects will take 20 mg once daily for 108 weeks during the treatment period.


Locations(1)

Guangdong Provincial People's Hospital

Guangzhou, Yuexiu District, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06819826


Related Trials