RecruitingNot ApplicableNCT06820606

Comparing Rezum and Urolift

A Randomized Controlled Trial Comparing Efficacy and Cost Effectiveness of Water Vapour Thermal Therapy (Rezum) and Prostatic Urethral Lift (UroLift) in Men With Benign Prostatic Hyperplasia


Sponsor

Chinese University of Hong Kong

Enrollment

120 participants

Start Date

Jan 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a randomized controlled trial using a non-inferiority design with the subjects randomized 1:1 to either water vapour thermal treatment (REZUM) arm or prostatic urethral lift (UroLift) arm.


Eligibility

Sex: MALEMin Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study compares two minimally invasive procedures — Rezum (steam treatment) and UroLift (a device that holds tissue out of the way) — for men with an enlarged prostate (benign prostatic hyperplasia, or BPH) causing urinary symptoms. **You may be eligible if...** - You are a male aged 50 or older - You have been diagnosed with BPH with significant urinary symptoms (IPSS score of 13 or above) - Your prostate size is between 30 and 80 mL **You may NOT be eligible if...** - You have a history of or high suspicion for prostate cancer - You have an active urinary tract infection - You have significant urine retention (residual urine over 250 mL) or can no longer urinate on your own - You have a large prostate lobe protruding into the bladder (intravesical prostatic protrusion over 10mm) - You have had previous prostate surgery - You have an allergy to nickel, titanium, or polyester - You have a urethral stricture, bladder neck contracture, or neurogenic bladder Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERezum

In the REZUM arm, water vapour treatment will be preformed.

DEVICEUroLift

In the UroLift arm, prostatic urethral lift treatment will be performed.


Locations(1)

Prince of Wales Hospital, The Chinese University of Hong Kong

Hong Kong, Hong Kong

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NCT06820606


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