RecruitingNCT06821243
Patients with Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical Intervention
Multidimensional Assessment of Virus-associated Head and Neck Cancer Patients for the Discovery of Predictive Biomarkers to Guide Clinical Intervention
Sponsor
Regina Elena Cancer Institute
Enrollment
40 participants
Start Date
Jul 24, 2024
Study Type
OBSERVATIONAL
Conditions
Summary
Prospective pilot study, non-interventional, of a biological/radiological nature, which involves the collection of tissue samples, and blood from patients suffering from squamous cell carcinoma of the oropharynx OPSCC for detection of HPV-DNA/RNA and immuno-phenotypic analysis of T cells, study of extracellular vesicles, and dosages of cytokines and chemokines involved in the immune response
Eligibility
Min Age: 18 Years
Inclusion Criteria4
- Squamous cell carcinomas of the oropharynx (OPSCC) candidates for surgical
- Age \> 18 years
- ECOG performance status \<\_ 2
- Signature of informed consent (to participate in the study and data processing)
Exclusion Criteria2
- Presence of distant metastases at the time of diagnosis
- Previous head and neck cancer
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06821243