RecruitingPhase 4NCT06823349

Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor

Comparative Analysis of Analgesic Efficacy and Maternal Satisfaction: Single Shot Intrathecal Bupivacaine With Fentanyl Versus Bupivacaine With Dexmedetomidine in Normal Labor, Randomized Control Clinical Trial


Sponsor

Jehan George Sadek

Enrollment

90 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Summary

the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and increasing duration of analgesia in normal labor.


Eligibility

Sex: FEMALE

Inclusion Criteria5

  • ASA I-II.
  • Uncomplicated pregnancy.
  • At term \& singleton fetus.
  • Cervical dilatation > 5cm
  • Cephalic presentations

Exclusion Criteria5

  • Patient refusal.
  • Bleeding disorders and patients on anticoagulant drugs.
  • Infection at site of injection.
  • Spine deformity.
  • Allergy to any of study medications.

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Interventions

DRUGDexmedetomidine

5 mic dexmedetomidine will be given intrathecally added to 2.5 mg bupivacaine

DRUGfentanyl

25 mic of fentanyl will be given intrathecally added to 2.5 mg bupivacaine

DRUGSaline 0.9%

0.5 ml of saline 0.9% will be given intrathecally added to 2.5 mg of bupivacaine


Locations(1)

Aswan University Hospital

Aswān, Egypt

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NCT06823349