Prediction of Risk of Vascular Structural Damage in Patients With Large Vessel Vasculitis (LVV) Based on PET/MRA Image Evaluation System
A Prospective, Observational Study on Prediction of Risk of Vascular Structural Damage in Patients With Large Vessel Vasculitis(LVV) Based on PET/MRA Image Evaluation System
Nanjing Medical University
150 participants
Jan 1, 2024
OBSERVATIONAL
Conditions
Summary
Large vessel vasculitis (LVV) causes vascular inflammation, leading to serious complications such as aneurysm formation and stroke. It is difficult to identify the inflammation of the vessel wall by the current imaging methods, thus affecting the timing of treatment and selection of treatment options. Improved examination methods to determine disease activity are highly needed to guide treatment.
Eligibility
Inclusion Criteria3
- Clinically suspected or confirmed LVV and willing to undergo PET/MRA
- Compliance with long-term follow-up
- Sign informed consent.
Exclusion Criteria7
- Patients with other serious cardiovascular and cerebrovascular diseases, malignant tumors, infectious diseases, severe renal insufficiency.
- Severe mental disorders, severe claustrophobia unable to cooperate with the examination.
- Patients equipped with cardiac pacemaker, artificial heart valve, ferromagnetic vascular clamp after vascular surgery, aneurysm clamp, artificial cochlea, insulin pump and other drug dosage control devices, steel nail plate and other metal internal fixation, artificial joint, electronic eye, artificial eye.
- Allergic to contrast medium.
- Pregnant or lactating women.
- Withdrawal criteria:
- Voluntarily withdrew from the study.
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Interventions
Drug intervention protocol will be determined by clinicians
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06824714