Long-Term Evaluation of TAILORED Vs Anatomical Ablation Strategy for Persistent Atrial Fibrillation

This long-term study is comparing two strategies for ablation (a procedure using heat or cold to destroy small areas of heart tissue that cause irregular rhythms) in people with atrial fibrillation (AFib): a tailored approach based on the individual's specific triggers versus a standard anatomical approach. **You may be eligible if...** - You are 18 or older - You have symptomatic atrial fibrillation that has not been controlled by medications - This is your first ablation procedure for AFib - You are in acceptable health for the procedure **You may NOT be eligible if...** - You have had a previous ablation for atrial fibrillation - You have severe structural heart disease (such as severe valve disease) - You have a blood clot in the left atrium of your heart - You have recently had a stroke or heart attack Talk to your doctor to see if this trial is right for you.