RecruitingPhase 1Phase 2NCT06826196

A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution in Subjects With Alopecia Areata

A Phase 1B/2A, Intraindividual Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution for Intradermal Injection in Subjects With Alopecia Areata


Sponsor

Aldena Therapeutics

Enrollment

24 participants

Start Date

Mar 24, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this first-in-human clinical trial is to learn if ALD-102 Solution is safe and well tolerated following injections in the scalp in subjects with alopecia areata. The study will also learn about the effect of ALD-102 on hair regrowth in treatment areas. The researchers will compare the effects of ALD-102 Solution (drug) to placebo (saline solution that contains no drug) or an untreated area. Study participants will have treatment areas selected on the scalp to receive ALD-102 Solution (drug), placebo (saline solution) or to remain untreated. Injections will occur once every 4 weeks for a treatment period of 8 weeks.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ALD-102 Solution and Placebo or Control for people with alopecia areata (aa). The study is currently recruiting participants at 7 locations. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGALD-102 Solution

Treatment every 4 weeks for total of 8-week treatment period.

OTHERPlacebo or Control

Treatment every 4 weeks for 8-week treatment period


Locations(7)

Clinical Trial Research Institute

Thousand Oaks, California, United States

Options Research Group

West Lafayette, Indiana, United States

The Brigham and Women's Hospital

Boston, Massachusetts, United States

Dermatology Specialists of Spokane

Spokane, Washington, United States

The Centre for Clinical Trials

Oakville, Ontario, Canada

Innovaderm

Montreal, Quebec, Canada

Centre de Recherche Saint-Louis

Québec, Quebec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06826196


Related Trials