7T Anatomo-functional Characterization of Structures in the Action Observation Network
More Than Cerebral Cortex: 7T Anatomo-functional Characterization of Cortical, Subcortical, and Cerebellar Structures Involved in THE Network of Action Observation
IRCCS Fondazione Stella Maris
40 participants
Dec 2, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical connectivity of the nodes of the AON circuit, using an ultra-high field (7T), high spatial resolution Magnetic Resonance Imaging protocol. The main questions it aims to answer are: * Can we demonstrate the involvement of subcortical areas and cerebellum in the AON circuit in each single-subject? * Can we obtain similar results in a small group of patients with Cerebral Palsy (CP), in order to demonstrate the feasibility of this approach for the study of the mechanisms of AON reorganization, after early brain damage? * Are different patterns of functional activation correlated to different clinical characteristics of CP patients? Participants will perform a 7 Tesla MRI scan, with a functional and anatomical dedicated protocol and will have a comprehensive clinical assessment before the MRI exam.
Eligibility
Plain Language Summary
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Interventions
a 7 Tesla MRI scan, with a functional and anatomical dedicated protocol
A comprehensive clinical assessment before the MRI exam.
Locations(2)
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NCT06826287