RecruitingNot ApplicableNCT06828159

Dietary Wild Blueberries and Joint Health

Effects of Dietary Wild Blueberries on Gut Health and Inflammation and Joint Pain


Sponsor

University of Nevada, Las Vegas

Enrollment

50 participants

Start Date

Sep 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this proposed study is to examine the effects of dietary wild blueberries on gut microbiome, serum markers of inflammation, and joint function in adults. Each participant will consume 25g freeze-dried blueberries or matched placebo powder for 12 weeks, with a 2-week washout phase between.


Eligibility

Min Age: 40 YearsMax Age: 75 Years

Inclusion Criteria1

  • Adults with documented multi-joint/knee arthritis

Exclusion Criteria11

  • inability to give informed consent
  • pregnancy or lactation
  • planned knee replacement surgery
  • allergy or contraindication to berries
  • recent trauma of the knee responsible of the symptomatic knee
  • intra-articular injection in the target knee/hip in the last 3 months
  • oral corticosteroid therapy ≥ 5 mg/day (prednisone equivalent) at baseline
  • use of berry extracts in the last 3 months
  • special diets
  • cancer treatment
  • bone diseases

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Interventions

DIETARY_SUPPLEMENTWild blueberry

Freeze-dried wild blueberry powder 25g/day

DIETARY_SUPPLEMENTPlacebo

Placebo powder matched for calories and no polyphenols


Locations(1)

OMRF

Oklahoma City, Oklahoma, United States

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NCT06828159


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