The Effect of Uterine Entry In Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
The Effect of Entry Technique on Chorioamniotic Membrane Separation in Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome
Baylor College of Medicine
216 participants
Mar 14, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate whether the entry technique surgeons use to get inside the uterus to perform fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome has an effect on the rates of chorioamniotic membrane separation.
Eligibility
Inclusion Criteria2
- Patients who are eligible and elect to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
- Patients will be between 16 0/7 weeks and 26 0/7 weeks gestational age.
Exclusion Criteria5
- Patients who do not elect to undergo fetoscopic laser photocoagulation for the treatment of complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
- Triplets and higher order multiple gestations.
- Patients who are less than 16 0/7 weeks or greater than 26 0/7 weeks gestational age.
- Patients with a short cervix (less than 1.5 cm).
- Patients with a known subchorionic hemorrhage.
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Interventions
Patients who choose to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome will be offered participation in the study. All participants will undergo selective laser photocoagulation and entry into the uterus will be achieved using one of two accepted methods, either direct entry or the Seldinger technique.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06829901