RecruitingNot ApplicableNCT06831292

The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm

Molecular Mechanisms for Male Fertility: Can Diet Change Sperm sncRNA and the Reproductive Potential?


Sponsor

Ostergotland County Council, Sweden

Enrollment

100 participants

Start Date

Dec 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-coding RNA profile. In our previous study sperm showed rapid response to diet.


Eligibility

Sex: MALEMin Age: 23 YearsMax Age: 56 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether a man's diet before IVF (in vitro fertilization) affects the tiny molecules in his sperm and ultimately the success of the IVF procedure. Participants will undergo a dietary intervention and researchers will analyze sperm samples before and after to look for changes. **You may be eligible if...** - You are the male biological partner in a couple about to start their first IVF treatment cycle - You have mature sperm cells present in a semen sample - You can read and speak Swedish - You currently eat an omnivore diet (meat and plant foods) - You are willing to abstain from nicotine and alcohol during the study **You may NOT be eligible if...** - You have or have had cancer - You have had radiation therapy to the pelvic area - You have had chemotherapy - You have a known genetic or chromosomal condition - You have a food allergy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTDiet intervention NMR

Participants will receive groceries to their homes with planned recipes. The recipes are planned by using the Nordic nutrition councils recommendations.


Locations(1)

University Hospital

Linköping, Östergötland County, Sweden

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NCT06831292


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