The Effects of Diet on Small Non-coding RNA I Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm
Molecular Mechanisms for Male Fertility: Can Diet Change Sperm SncRNA and the Reproductive Potential?
Ostergotland County Council, Sweden
100 participants
Dec 26, 2024
INTERVENTIONAL
Conditions
Summary
In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines. The purpose is to investigate whether a short diet intervention is sufficient to improve sperm quality and shift the small non-coding RNA profile. In our previous study sperm showed rapid response to diet.
Eligibility
Inclusion Criteria6
- Male (biological) partner in infertile couple, scheduled for first IVF treatment
- Mature sperm cells in semen
- Able to speak and read Swedish
- Omnivore
- Will refrain from nicotine and alcohol during intervention
- Sperm sampled provided no more than 3 weeks before intervention start
Exclusion Criteria5
- Former or present malignant disease
- Former radiotherapy in pelvic area
- Former chemotherapy
- Known genetic/chromosomal disorder
- Food allergy
Interventions
Participants will receive groceries to their homes with planned recipes. The recipes are planned by using the Nordic nutrition councils recommendations.
Locations(1)
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NCT06831292