RecruitingNCT06833762

Clinical and CPET Parameters That Predict Improvement in Functional Capacity After TAVI

Determining Clinical and Cardiopulmonary Exercise Testing Parameters That Predict Improvement in Functional Capacity and Complications After Transcatheter Aortic Valve Implantation

Sponsor

Hospital Clinic of Barcelona

Enrollment

161 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Aortic Stenosis Disease

Summary

Determining Clinical and Cardiopulmonary exercise testing Parameters that may predict Improvement in Capacity After Transcatheter Aortic Valve Implantation

Eligibility

Min Age: 18 Years

Inclusion Criteria2

All those patients ≥ 18 years of age with severe aortic stenosis approved for transfemoral TAVI.
Both sexes, male and female will be included in the study.

Exclusion Criteria10

Very severe aortic stenosis, defined as a valve area of ≤0.6 cm2
, mean gradient ≥60 mmHg or Vmax >5 m/s
Previous syncope
Proven exercise-induced arrhythmias
Previously known dynamic left ventricular outflow tract (LVOT) obstruction, defined as LVOT gradient of ≥ 30 mmHg by echocardiography
Concomitant coronary artery disease pending percutaneous coronary intervention
Inability to consent
Physical limitation to perform an exercise test
Non-elective procedure
Valve-in-valve procedure