RecruitingPhase 4NCT06834594

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome: A Non-randomized Prospective Trial (The BOOST Study)

Sponsor

Children's Mercy Hospital Kansas City

Enrollment

40 participants

Start Date

Jul 31, 2025

Study Type

INTERVENTIONAL

Conditions

Turner Syndrome Primary Ovarian Insufficiency (Poi)

Summary

This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).

Eligibility

Sex: FEMALEMin Age: 12 YearsMax Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Micronized Progesterone 100 MG and a drug called Micronized progesterone 200 MG for people with primary ovarian insufficiency (poi) and turner syndrome. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 12 Years to 20 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMicronized progesterone 200 MG

Oral micronized progesterone 200mg for the first 12 days of a 30 to 31-day cycle

DRUGMicronized Progesterone 100 MG

Oral micronized progesterone 100mg daily taken throughout the 30 to 31-day cycle.

Locations(1)

Children's Mercy Hospital

Kansas City, Missouri, United States

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NCT06834594

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