RecruitingNCT06835218

PROCARE - PROstate Cancer Real World Evidence Registry

PROstate CAncer Real World Evidence Registry: RECURRENT AND METASTATIC PROSTATE CANCER


Sponsor

UroTrials Company (GmbH)

Enrollment

5,000 participants

Start Date

Jan 29, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this registry study with long-term follow-up is to record the course of therapy and disease in patients with recurrent and metastatic prostate cancer. The following patient groups are planned: * Patients with a recurrence of PSA after surgical removal or radiation of the prostate due to prostate cancer; so-called PSA recurrence (relapse) or biochemical recurrence. * Patients with a PSA recurrence who have received treatment by hormone deprivation therapy (so-called androgen deprivation) and in whom the PSA value has nevertheless risen again without spreading to other organs or parts of the body, so-called non-metastatic castration-resistant prostate cancer. * Patients with proven spread to other organs or parts of the body (= metastases, e.g. in the bone) without hormone deprivation therapy having been initiated, so-called metastatic hormone-sensitive prostate cancer. * Patients with prostate cancer and spread to other organs or parts of the body (= metastases) in whom the tumor disease has progressed despite hormone withdrawal treatment (e.g. as evidenced by an increase in PSA), so-called metastatic castration-refractory prostate cancer. These four groups of patients are enrolled and observed independently of each other at different time periods.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

PROCARE is a real-world registry study that collects data from prostate cancer patients at different stages of the disease — from biochemical recurrence (rising PSA after prior treatment) to metastatic castration-resistant prostate cancer — to better understand how treatments work in everyday clinical practice. **You may be eligible if...** - You are 18 or older with a diagnosis of prostate cancer - You fall into one of these categories: PSA rising after prior curative treatment; non-metastatic castration-resistant disease; metastatic hormone-sensitive disease; or metastatic castration-resistant prostate cancer - You are starting a new line of systemic treatment at the time of enrollment or within 4 weeks **You may NOT be eligible if...** - You do not fit into any of the disease categories above - You are not starting or on systemic therapy - You are unable or unwilling to participate in long-term follow-up Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(53)

Universitätsklinikum Freiburg

Freiburg im Breisgau, Baden-Wurttemberg, Germany

National Center for Tumor Dieseases (NCT) Heidelberg

Heidelberg, Baden-Wurttemberg, Germany

University Hospital Mannheim

Mannheim, Baden-Wurttemberg, Germany

Medical Office for Urology Nürtingen

Nürtingen, Baden-Wurttemberg, Germany

Studienpraxis Urologie

Nürtingen, Baden-Wurttemberg, Germany

University Hospital Tübingen

Tübingen, Baden-Wurttemberg, Germany

University Hospital Ulm

Ulm, Baden-Wurttemberg, Germany

University Hospital Augsburg

Augsburg, Bavaria, Germany

University Hospital Augsburg

Augsburg, Bavaria, Germany

Hospital Bayreuth GmbH

Bayreuth, Bavaria, Germany

University Hospital Erlangen

Erlangen, Bavaria, Germany

Hospital Kempten

Kempten (Allgäu), Bavaria, Germany

Hospital Nürnberg North

Nuremberg, Bavaria, Germany

Caritas-Hospital St. Josef

Regensburg, Bavaria, Germany

University Hospital Würzburg

Würzburg, Bavaria, Germany

"Vivantes Prostatazentrum" Hospital "am Urban"

Berlin, Brandenburg, Germany

University Hospital Hamburg-Eppendorf

Hamburg, Free and Hanseatic City of Hamburg, Germany

University Hospital Frankfurt/Main

Frankfurt am Main, Hesse, Germany

Universitiy Hospital Gießen und Marburg GmbH, Site: Gießen

Giessen, Hesse, Germany

Universital Hospital Gießen & Marburg GmbH, Site: Marburg

Marburg, Hesse, Germany

Hospital Wetzlar

Wetzlar, Hesse, Germany

Medical Office for Urology

Braunschweig, Lower Saxony, Germany

Medical Office for Urology

Herzberg am Harz, Lower Saxony, Germany

St. Bernward Hospital Hildesheim

Hildesheim, Lower Saxony, Germany

St. Bernward Krankenhaus GmbH

Hildesheim, Lower Saxony, Germany

Medical Office for Urology Altstadtquartier Magdeburg

Magdeburg, Lower Saxony, Germany

MVZ Onco Medical GmbH Neustadt

Neustadt am Rübenberge, Lower Saxony, Germany

Praxisgemeinschaft f. Onkologie & Urologie

Wilhelmshaven, Lower Saxony, Germany

University Hospital Rostock

Rostock, Mecklenburg-Vorpommern, Germany

University Hospital Aachen

Aachen, North Rhine-Westphalia, Germany

Medical Office for Urology

Bayenthal, North Rhine-Westphalia, Germany

Marien Hospital Bergisch Gladbach,

Bergisch Gladbach, North Rhine-Westphalia, Germany

Johanniter GmbH, Johanniterkrankenhaus

Bonn, North Rhine-Westphalia, Germany

Johanniter Hosptal Bonn

Bonn, North Rhine-Westphalia, Germany

University Hospital Bonn

Bonn, North Rhine-Westphalia, Germany

Medical Office for Urology "Urologicum"

Duisburg, North Rhine-Westphalia, Germany

University Hospital Düsseldorf

Düsseldorf, North Rhine-Westphalia, Germany

University Hospital Essen

Essen, North Rhine-Westphalia, Germany

Marien Hospital Herne, University Hospital der Ruhr-Universität Bochum

Herne, North Rhine-Westphalia, Germany

"Brüder" Hospital St. Joseph Paderborn

Paderborn, North Rhine-Westphalia, Germany

University Hospital Wuppertal

Wuppertal, North Rhine-Westphalia, Germany

Medical Office for Urology

Würselen, North Rhine-Westphalia, Germany

Urban Hospital Karlsruhe

Karlsruhe, Rhineland-Palatinate, Germany

Hospital "Barmherzigen Brüder "Trier

Trier, Rhineland-Palatinate, Germany

Center for Urology Boxberg

Neunkirchen, Saarland, Germany

University Hospital Leipzig

Leipzig, Saxony, Germany

City Hospital Dessau

Dessau, Saxony-Anhalt, Germany

Universitiy Hospital Halle

Halle, Saxony-Anhalt, Germany

University Hospital Halle

Halle, Saxony-Anhalt, Germany

Urologie Altstadtquartier Magdeburg

Magdeburg, Saxony-Anhalt, Germany

University Hospital Magdeburg

Magdeburg, Saxony-Anhalt, Germany

Univerity Hospital Schleswig-Holstein

Lübeck, Schleswig-Holstein, Germany

University Hospital Jena

Jena, Thuringia, Germany

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06835218


Related Trials