Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography
Centre Hospitalier William Morey - Chalon sur Saône
60 participants
Jun 3, 2024
OBSERVATIONAL
Conditions
Summary
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality. It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias. The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.
Eligibility
Inclusion Criteria3
- Patient or relative informed of the study and having declared their non-objection
- Patient over 18 years old
- Patient hospitalized in ICU with an arterial catheter
Exclusion Criteria4
- Patient unable to express consent
- Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible
- Patient with arterial catheter removed outside the usual procedure of the ICU
- Patient admitted in ICU with an arterial catheter already in place
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Interventions
Dynamic full-field optical coherence tomography (D-FF-OCT) analysis of arterial catheter sections before microbiological analysis of catheter biofilm
Locations(2)
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NCT06838598