Ultrasonographic Patterns and Pathological Correlation in the Diagnosis of Subcutaneous Nodules

This study is looking at whether ultrasound images of skin lumps (called subcutaneous nodules) can predict what type of tissue problem is causing them before doing a biopsy. The goal is to help doctors diagnose conditions like panniculitis (inflammation in the fat layer under the skin) more accurately. **You may be eligible if...** - You are 18 years old or older - You have a skin lump (subcutaneous nodule) that needs a biopsy for diagnosis - The lump is in a location where a tissue sample can safely be taken - You have signed the consent form agreeing to participate **You may NOT be eligible if...** - Your lump appears to be caused by simple conditions that mimic panniculitis (like a painful lipoma or cellulitis) - You have a disease that significantly changes skin structure (like scleroderma or severe swelling) - You have had previous treatments in the area of the lump (such as surgery, radiation, or high-dose steroids) Talk to your doctor to see if this trial is right for you.