A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies
A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AWT020 Alone and in Combination With Other Antitumor Therapies in Patients With Advanced Malignancies
Shanghai Junshi Bioscience Co., Ltd.
214 participants
Feb 21, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this phase I clinical study was to evaluate the safety and tolerability of AWT020 monotherapy and combination with other antitumor therapies in patients with advanced malignancies
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
135\~175 mg/m2, Q3W
Cisplatin(75 mg/m2, Q3W) or Carboplatin (AUC=5\~6, Q3W)
500 mg/m2, Q3W
130 mg/m2, Q3W
1000 mg/m2, BID, day1-14, oral, q3w
7.5 mg/kg, Q3W
8mg or 20mg, QD
q3w or q2w, i.v.
Locations(13)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06839105