Effect of St. John's Wort in the Treatment of Recurrent Aphthous Stomatitis
Comparative Evaluation of the Effect of Hypericum Perforatum on Pain Level in the Treatment of Recurrent Aphthous Stomatitis:A Randomized Clinical Trial
Batman University
75 participants
Feb 1, 2025
INTERVENTIONAL
Conditions
Summary
The aim of the treatment of Recurrent Aphthous Stomatitis (RAS) is to accelerate the healing of ulcers by reducing pain and inflammation, thus enabling patients to perform their oral functions comfortably. It has been said many times in the literature that St. John's wort is very effective in wound healing.In this study, the evaluation of the therapeutic effects of St. John's wort extract on the clinical symptoms and ulcer healing rate in patients with Recurrent Aphthous Stomatitis (RAS), a condition with no definitive treatment, was aimed.
Eligibility
Inclusion Criteria4
- 18 years and over
- Having a history of RAS for at least 2 years
- Having one in an easily accessible area in the mouth
- RAS has not exceeded a period of 48 hours
Exclusion Criteria4
- Having any allergic history to these substances to be applied
- During pregnancy and lactation
- Use of steroids, vitamins, antibiotics, antihistamines, oral retinoids or immune system regulating agents for ulcer treatment within 3 months
- The patient has a history of systemic disease
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Interventions
Apply to the injured area 4 times a day
Apply to the injured area 4 times a day
Apply to the injured area 4 times a day
Locations(1)
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NCT06839313