Clinical Study of Carbon Ion Radiotherapy for Pancreatic Cancer.

This study is testing carbon ion radiotherapy (a precise, high-energy form of radiation) combined with chemotherapy (gemcitabine plus a targeted antibody) for people with locally advanced or metastatic pancreatic cancer. Carbon ion therapy delivers radiation more precisely than standard X-ray radiation, potentially killing more cancer cells with less damage to surrounding tissue. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with locally advanced or metastatic pancreatic adenocarcinoma (stage III or IV) confirmed by lab tests - You have at least one measurable tumor on scans - Your liver, kidney, and blood counts are within acceptable limits **You may NOT be eligible if...** - You have had another cancer (except cured skin cancer or early-stage cervical cancer) - Your organ function is too impaired - You are pregnant or breastfeeding - You have other serious medical conditions that would make treatment unsafe Talk to your doctor to see if this trial is right for you.