Contribution of New Pancreatic MRI Sequences for the Evaluation of Tumor Response in Pancreatic Adenocarcinomas
Central Hospital, Nancy, France
120 participants
Jun 6, 2025
INTERVENTIONAL
Conditions
Summary
Pancreatic adenocarcinoma is the most pessimistic digestive cancer in terms of prognosis. Tumor response assessment is crucial, and the recent development of new magnetic resonance imaging sequences, such as high resolution applied to diffusion sequences (Harder et al., 2022) or magnetic resonance elastography (MRE) (Steinkohl et al., 2021), could help address this issue.
Eligibility
Inclusion Criteria4
- CT scan diagnosis of non-metastatic pancreatic cancer on contrast-enhanced thoraco-abdomino-pelvic CT;
- Adult patient: age ≥ 18 years;
- Patient affiliated with a social security system or beneficiary of such a system;
- Patient who has received complete information about the research organization and has signed an informed consent form.
Exclusion Criteria7
- Patient with a contraindication to MRI.
- Person referred to in Articles L. 1121-5, L. 1121-7, and L. 1121-8 of the French Public Health Code.
- Pregnant woman, parturient, or breastfeeding mother;
- Minor (non-emancipated) individual;
- Adult individual under legal protection (guardianship, curatorship, or judicial safeguard);
- Adult individual unable to express consent.
- Person deprived of liberty by a judicial or administrative decision, or person undergoing psychiatric care pursuant to Articles L. 32-12-1 and L. 3213-1 of the French Public Health Code.
Interventions
Magnetic resonance elastography (MRE) is an imaging technique that measures tissue stiffness by assessing the deformation waves produced under external pressure
High-resolution diffusion sequence in MRI is an imaging technique that uses the movement of water molecules within tissues to generate detailed images.
Locations(1)
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NCT06842303