RecruitingPhase 3NCT06846086

Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy

A Clinical Study to Assess the Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy


Sponsor

Tanta University

Enrollment

46 participants

Start Date

Feb 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of current study is to: Evaluate the cardioprotective effects of melatonin in patients with cardiomyopathy.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients (≥18 years) with a confirmed diagnosis of cardiomyopathy based on clinical, echocardiographic, or imaging findings. .
  • Stable condition on standard cardiomyopathy medications (e.g., ACE inhibitors, beta-blockers).
  • Ability to provide informed consent.

Exclusion Criteria7

  • Recent hospitalization for cardiomyopathy exacerbation (within the last 3 months).
  • Severe kidney or liver impairment.
  • Use of other investigational drugs or antioxidants.
  • Pregnancy or planning to be pregnant in the next 6 months
  • Previous known hypersensitivity to melatonin.
  • Presence of atrial fibrillation or other significant arrhythmias at baseline.
  • Participation in another research.

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Interventions

DRUGMelatonin 10 MG

Melatonin

DRUGPlacebo

placebo


Locations(1)

Mansoura University Hospital

Dakahlia, Egypt, Mansoura, Egypt

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NCT06846086


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