To Perform a Post-market Study of the Performance of the Idylla ThyroidPrint Assay Using Clinical Samples in Predicting the Nature of Indeterminate Thyroid Nodules (ITNs) Across Multiple Centers.

This study is evaluating the performance of a molecular test called the Idylla ThyroidPrint Assay, which analyzes a small sample taken from a thyroid nodule (lump in the thyroid) to help doctors determine whether the nodule is cancerous — particularly when the standard cytology result comes back 'indeterminate' (unclear). **You may be eligible if...** - You have a thyroid nodule that is at least 1.0 cm in size - The initial biopsy (fine needle aspiration) returned an indeterminate (unclear) result - You are scheduled for surgery to remove the nodule **You may NOT be eligible if...** - Your biopsy result was clearly benign or clearly malignant - Your thyroid nodule is smaller than 1.0 cm - Your biopsy sample was preserved in formalin or alcohol (incompatible with the test) - Imaging shows suspicious lymph nodes in the neck suggesting cancer has spread - Your sample consists only of RNA extracts Talk to your doctor to see if this trial is right for you.