Development of Biomarkers for Monitoring Menopause in Women
Fu Jen Catholic University Hospital
100 participants
Jul 30, 2024
OBSERVATIONAL
Conditions
Summary
This cross-sectional study aims to develop and validate mitochondrial biomarkers for monitoring menopause in women. The study will involve 100 participants divided into three groups: reproductive period, perimenopausal transition period, and postmenopausal period. Peripheral blood samples will be collected, and mitochondrial quality and quantity will be assessed using both qualitative and quantitative analyses. The study will identify potential biomarkers through metabolomics and validate them for monitoring the perimenopausal transition, providing a novel approach for women's health management during menopause.
Eligibility
Inclusion Criteria1
- Biological female, age order than 20 years old.
Exclusion Criteria5
- Person with cancer.
- Person with any known acute or chronic infection.
- Person with known chronic illness under follow up or treatment.
- Pregnancy, one year withing delivery, under breast feeding, or three months within breast feeding.
- Under any female horemone therapy.
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Interventions
Collection of peripheral blood samples for mitochondrial analysis, including the extraction of mononuclear cells and plasma for further assessment of mitochondrial quality and quantity.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06852755