RecruitingPhase 3NCT06853951

Cardioprotection on Chemotherapy-Induced Cardiotoxicity

The Effect of Cardioprotective Medications on Chemotherapy-Induced Cardiotoxicity in Childhood Acute Leukemia


Sponsor

Ain Shams University

Enrollment

30 participants

Start Date

Jul 18, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the present study is to evaluate the protective impact of cardioprotective medications on the chemotherapy- induced cardiotoxicity.


Eligibility

Min Age: 1 YearMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether heart-protective medications can prevent heart damage in children and teenagers who are receiving chemotherapy known to cause heart toxicity. **You may be eligible if:** - You are between 2 and 18 years old - You have been diagnosed with cancer and are receiving chemotherapy - Your parent or legal guardian is willing to give informed consent - You are able to take oral (by mouth) medication **You may NOT be eligible if:** - You have a known allergy to heart-protective medications being studied Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGACE Inhibitors

0.3 mg/kg/dose every 8 hours orally by either a caregiver or caring nurse.

DRUGβ -Blockers

0.05 mg/kg/dose every 12 hours orally by either a caregiver or caring nurse.


Locations(2)

Faculty of Pharmacy, Ain Shams University

Cairo, Egypt

Faculty of Pharmacy, Ain Shams University

Cairo, Egypt

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NCT06853951


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