RecruitingNCT06854848

Cohort of Patients With Systemic Granulomatosis and Associated Biological Collection

Cohort of Patients With Systemic Granulomatosis (Sarcoidosis and Other Systemic Granulomatoses) and Associated Biological Collection GRAMI-BIO Study

Sponsor

University Hospital, Bordeaux

Enrollment

150 participants

Start Date

Dec 4, 2025

Study Type

OBSERVATIONAL

Conditions

Granulomatosis

Summary

The GRAMI-BIO study is a prospective single-centre cohort study to recruit 150 patients followed up in the the Bordeaux University Hospital. The total duration of the GRAMI-BIO study is ten years (five years of inclusion with five years of follow-up): Consecutive inclusion of patients meeting the definition of systemic granulomatosis. The main objective of this cohort is to describe to clinical progression of systemic granulomatosis and to collect blood fraction samples (serum bank, plasma bank, urine bank, DNA bank) from subjects participating in the cohort.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Patients aged 18 or over
Patients with systemic granulomatosis (diagnosis proven by anatomopathological sampling) at diagnosis.
Persons affiliated to or benefiting from a social security scheme.
Free, informed and written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research).

Exclusion Criteria4

Patients infected with human immunodeficiency virus (HIV), Hepatitis B virus (HBV) and/or Hepatitis C virus (HCV)
Pregnant or breast-feeding women
Patients already receiving specific treatment for systemic granulomatosis
Persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent.

Print for Your Doctor

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BIOLOGICALblood sample

30 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation

BIOLOGICALurine sample

10 ml

Locations(1)

CHU de Bordeaux - service de Médecine Interne et Immunologie Clinique

Bordeaux, France

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06854848