Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma

This early-phase study is testing the safety and dosing of a new treatment called RR001 given by injection directly into a tumor, combined with chemotherapy, for people with locally advanced pancreatic cancer that cannot be surgically removed. **You may be eligible if...** - You have confirmed pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) that is locally advanced and cannot be surgically removed - There is no evidence of spread to other organs - You have at least one tumor lesion of 3.5 cm or smaller that can be reached by ultrasound-guided injection - You are in good enough health to receive chemotherapy (ECOG 0–2) **You may NOT be eligible if...** - Your cancer has already spread beyond the pancreas to distant organs - Your tumor is too large or not accessible for direct injection - You are in poor overall health Talk to your doctor to see if this trial is right for you.