Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments

This study is exploring whether liver transplantation is a viable treatment option for people with a type of liver cancer called intrahepatic cholangiocarcinoma (iCCA) that cannot be surgically removed but has responded well to prior treatments like chemotherapy or immunotherapy. **You may be eligible if...** - You are between 18 and 70 years old - You have a confirmed diagnosis of intrahepatic cholangiocarcinoma (iCCA) by biopsy - Your tumor cannot be removed by surgery (due to location or underlying liver disease) - Your cancer has not spread to blood vessels or distant organs - Your cancer has shown a sustained response to prior treatments **You may NOT be eligible if...** - Your cancer has spread to blood vessels or outside the liver - You have had a prior liver transplant - Your cancer is progressing despite treatments Talk to your doctor to see if this trial is right for you.