RecruitingPhase 4NCT06864403

Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch


Sponsor

University of North Carolina, Chapel Hill

Enrollment

25 participants

Start Date

Aug 12, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if mirikizumab works to treat pouch disorders in adults. The main questions it aims to answer are: Does mirikizumab reduce symptoms of pouch disorders Participants will: Take mirikizumab every 4 weeks for one year Visit the clinic once every month for two months and at the end of the study Keep a diary of their symptoms


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Mirikizumab - Intravenous (IV) and a drug called Mirikizumab - Subcutaneous (SC) for people with pouch, ileal, pouches, ileoanal, and other related conditions. The study is currently recruiting participants at 5 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMirikizumab - Intravenous (IV)

300 mg mirikizumab at Weeks 0, 4, and 8

DRUGMirikizumab - Subcutaneous (SC)

Pre-filled syringes administered at Weeks 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, and 52.


Locations(5)

UCLA Vatche & Tamar Manoukian Division of Digestive Diseases

Los Angeles, California, United States

Mayo Clinic

Rochester, Minnesota, United States

NYU Langone Health

New York, New York, United States

University of North Carolina

Chapel Hill, North Carolina, United States

Allegheny Health Network

Pittsburgh, Pennsylvania, United States

View Full Details on ClinicalTrials.gov

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NCT06864403


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