RecruitingPhase 4NCT06866691

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

Seizure Prevention in Traumatic Brain Injury: A Comparative Effectiveness Study of Levetiracetam and Lacosamide


Sponsor

Wake Forest University Health Sciences

Enrollment

600 participants

Start Date

Apr 18, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess the incidence of early post-traumatic seizures. The study will also assess the benefit of lacosamide compared to levetiracetam in regards to agitation and behavioral adverse effects in patients with traumatic brain injury requiring seizure prophylaxis.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called lacosamide and a drug called levetiracetam for people with traumatic brain injury. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGlevetiracetam

levetiracetam 1000 mg intravenously or by mouth twice daily for a total of 7 days

DRUGlacosamide

lacosamide 200 mg intravenously or by mouth twice daily for a total of 7 days


Locations(1)

Wake Forest University Health Sciences

Winston-Salem, North Carolina, United States

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NCT06866691


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