RecruitingNot ApplicableNCT06867302

Dexmedetomidine and Agitation After Nasal Surgery

Effectiveness of Single Bolus Versus Continuous Infusion of Dexmedetomidine in Mitigating Agitation in Adults Undergoing Nasal Surgery: a Prospective Randomized Trial


Sponsor

Fayoum University Hospital

Enrollment

50 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective of study is to compare dexmedetomidine single bolus dose before extubation with continuous infusion as regards their efficacy in mitigating the incidence of emergence agitation in obese adults undergoing nasal surgery.


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Inclusion Criteria3

  • American Society of Anesthesiologist (ASA) Ⅰ or II
  • Adults with body mass index (BMI) \< 30 Kg/m
  • Underwent elective nasal surgery.

Exclusion Criteria6

  • Significant comorbidity like hepatic, renal, or cardiac disease
  • Auditory impairment
  • Cognitive dysfunction
  • Substance abuse
  • Allergy to the studied medicines
  • Planned intensive care admission after the surgery.

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Interventions

DRUGDexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)

An infusion given all through intraoperative time

DRUGDexmedetomidine Injection [Precedex]

Single dose given 15 minutes before end of surgery


Locations(1)

Fayoum University Hospital

Al Fayyum, Faiyum Governorate, Egypt

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NCT06867302


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