RecruitingNot ApplicableNCT06868771

Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated with Anti-EGFR

Studio Sulla Efficacia Di Una Crema Emolliente Contenente Pre E Postbiotici E Niacinamide 4% Nel Trattamento Della Xerosi Cutanea E Del Prurito in Pazienti Oncologici in Trattamento Con Anti-EGFR


Sponsor

Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse

Enrollment

164 participants

Start Date

Jul 29, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated With Anti-EGFR.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • patients aged 18 who have been receiving anti-EGFR therapy for more than three months,
  • signature of the informed consent.

Exclusion Criteria4

  • Patients diagnosed with Grade II papulopustulous skin reaction according to the Common Terminology Criteria for Adverse Event (CTCAE) scale at the time of enrolment;
  • concomitant use of emollients and/or steroidal creams;
  • personal history of xerotic pathologies (e.g. lichen, ichthyosis) and/or itching of n.d.d.;
  • inability to provide informed consent or inability to complete the procedures required for enrollment in the study.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERtopical treatment with the pre- and postbiotic study preparation and niacinamide 4% and one with the 10% urea-based preparation.

Application of the topical preparation in both groups will be performed twice a day for a total duration of 3 months.


Locations(1)

Irccs Fondazione Policlinico Gemelli

Roma, ROMA, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06868771


Related Trials