RecruitingNCT06868927

Targeted Decision Making In Renal Cell Carcinoma Relying on a Radiogenomics Translational Platform

Sponsor

IRCCS San Raffaele

Enrollment

50 participants

Start Date

Sep 26, 2025

Study Type

OBSERVATIONAL

Conditions

Renal Tumors

Summary

This project aims to provide an accurate strategy to guide the decision making relying on tumor biopsies using standard histology, immunohistochemistry (IHC), spatial transcriptomics, genomics combined with Magnetic Resonance Imaging (MRI) and radiomics. Moreover, the investigators will explore potential markers indicative of response to systemic agents or ablative therapy.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring whether combining imaging scans (MRI) with genetic tumor analysis can help doctors make better treatment decisions for people with small kidney tumors. The goal is to predict whether a kidney mass is cancerous without needing extensive surgery. **You may be eligible if...** - You are 18 years old or older - You have a kidney mass or tumor that is 4 centimeters (about 1.5 inches) or smaller - You are scheduled for kidney surgery - You are willing to provide informed consent **You may NOT be eligible if...** - You cannot have an MRI scan (for example, if you have a pacemaker or certain metal implants) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

IRCCS Ospedale San Raffaele

Milan, Italia, Italy

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NCT06868927

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