RecruitingNCT06869122

Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates - UK

Assessment of the Safety and Performance of the AB1 Electrosurgical System for Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates - UK


Sponsor

Creo Medical Limited

Enrollment

18 participants

Start Date

Jul 14, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study involves the use of a medical device, the Creo Medical MicroBlate Flex instrument, to heat and destroy lung tumour cells using microwave energy (this is also called ablation). In this study, the investigators are investigating whether the ablation instrument can be used effectively to treat lung tumours or tumours that have spread to the lungs. If successful, using this technology may mean future patients may not need to undergo surgical removal of these types of lung tumours. The aim of this study is to evaluate the safety and performance of the MicroBlate Flex instrument in treating individuals with cancerous lung tumours that are due to be removed by surgery. All participants in the study will undergo the microwave ablation procedure, which is a separate and additional procedure to their surgical procedure. The study, funded by Creo Medical, will be conducted at sites in the UK and Italy, and will involve up to 18 participants.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing bronchoscopic microwave ablation — a minimally invasive procedure that uses heat delivered through a flexible tube inserted into the airways — to destroy small lung cancer tumors. It is designed for people who are suitable for surgery but might benefit from this less invasive option. **You may be eligible if...** - You are 18 years old or older - Your lung cancer has been confirmed by biopsy - Your tumor is small (2 centimeters or less at its widest point) - A team of specialists has determined you could have surgery to remove the tumor - There is a safe margin of healthy lung tissue between the tumor and the chest wall or lung lining - You are in generally good health and can tolerate general anesthesia **You may NOT be eligible if...** - The tumor is located near critical structures such as major blood vessels, the heart, airways, or spinal cord - You are pregnant or breastfeeding - You have participated in another experimental treatment study within the past 30 days Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEAblation

Bronchoscopy and microwave ablation of the lung tumour prior to surgical resection.


Locations(2)

Istituto Europeo di Oncologia (IEO), Via Ripamonti 435

Milan, Italy

Royal Brompton and Harefield NHS Foundation Trust, Royal Brompton Hospital, Sydney Street

London, UK, United Kingdom

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06869122


Related Trials