RecruitingNot ApplicableNCT06872515

Impact of Prehabilitation in Oncology Via Exercise- Esophageal (IMPROVE-Esophageal)

Impact of Prehabilitation in Oncology Via Exercise- Esophageal


Sponsor

University of Pittsburgh

Enrollment

20 participants

Start Date

Jul 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to determine the feasibility of a prehabilitation exercise and nutrition program (exercise and nutrition before a medical treatment) in adults with esophageal cancer before surgery (esophagectomy). The pre-surgery exercise and nutrition program will include resistance and aerobic training and nutrition supplementation during the weeks before surgery. We will also assess pre-surgical care needs in adults with esophageal cancer. Researchers will compare the exercise and nutrition intervention to usual care- which is standard medical care and post-surgery surveillance/follow-up to understand the impact of exercise and nutrition before surgery. We will follow-up with participants before surgery, and after surgery at 2 weeks, 6 weeks, and 4-months at appointments that coincide with clinical follow-ups. The main questions of this trials are: * Is exercise and nutrition supplementation before surgery for esophageal cancer feasible and acceptable to patients? * How does exercise and nutrition supplementation before surgery change physical function and psychosocial health? * What are important pre-surgical needs for adults with esophageal cancer?


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a structured exercise program before esophageal cancer surgery (called prehabilitation) can improve patients' physical fitness and help them recover better after the operation. **You may be eligible if...** - You are 18 years old or older - You have been diagnosed with esophageal cancer - You are scheduled to have esophageal surgery (esophagectomy) at Hillman Cancer Center or UPMC Shadyside - Your surgery is at least 2 weeks away - You are in good enough health to exercise (ECOG score of 2 or below) - You can understand and speak English **You may NOT be eligible if...** - You have a medical condition that makes exercise unsafe (for example, severe heart failure or uncontrolled high blood pressure) - You have other physical conditions preventing exercise participation - You are receiving chemotherapy or radiation for reasons unrelated to your esophageal cancer - You have active infections or blood complications that could put you at risk Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExercise and Nutrition

The exercise and nutrition intervention will last up to 8 weeks and will include: * 3-5 times per week of resistance training and 3-5 times per week of aerobic training. The prescribed exercise will be personalized based on the participant's baseline functionality. * Ensure Complete nutrition supplement drinks: 2 per day starting on the same day the exercise begins, up until 5 days prior to surgery.

BEHAVIORALUsual Care Group

The CONT group will not receive any intervention during study participation and undergo usual medical treatment and surveillance during the duration of the study.


Locations(1)

UPMC Hillman Cancer Center

Pittsburgh, Pennsylvania, United States

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NCT06872515


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