RecruitingNot ApplicableNCT06876948

NENCA Study on Neurological Complications of Long COVID-19 in Children and Adolescents; Neurophysiological, Electroencephalographic and Neuroradiological Investigation

STUDY of NEUROLOGICAL COMPLICATIONS of LONG COVID-19 in CHILDREN and ADOLESCENTS; NEUROPSYCHIATRIC, ELECTROENCEPHALOGRAPHIC and NEURORADIOLOGICAL INVESTIGATIONS

Sponsor

Azienda Ospedaliero, Universitaria Pisana

Enrollment

100 participants

Start Date

Mar 29, 2023

Study Type

INTERVENTIONAL

Conditions

Long Covid 19

Summary

The study seeks to investigate the neurological effects caused by Covid-19 in children and adolescents in the 6-16 age group. To do this, neuropsychological scales, an EEG and an MRI were used.

Eligibility

Min Age: 6 YearsMax Age: 16 Years

Inclusion Criteria3

Age between 6 years and 16 years and 11 months
Symptomatology compatible with long neurological COVID, specifically: persistence or appearance of new neurological signs/symptoms (e.g. fatigue, headache, sleep disturbance, cognitive dysfunction, memory difficulties, emotional or mood disorders, vertigo cognitive dysfunction, memory difficulties, emotional or mood disorders, dizziness, dysautonomia, movement disorders movement disorders, ataxia, tremor, epilepsy, muscle weakness, myalgia, hyposmia, hypogeusia hearing loss or tinnitus and/or sensorimotor deficits such as hypoesthesia, dysesthesia) after three months after established SARS-CoV-2 infection, as well as persistence of these symptoms for at least two months, in the absence of a clear aetiology.
Signature of the appropriate Informed Consent by caregiver(s) and patient(s)

Exclusion Criteria4

Poor knowledge of the Italian language or other limitation of verbal communication that compromises the subject's ability to perform neuropsychological tests
Need for sedation to perform brain MRI 7 Tesla
Neurological or neuropsychiatric disorder diagnosed prior to COVID-19 diagnosis
Caregiver's failure to sign consent

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Interventions

DIAGNOSTIC_TESTPsychological tests, EEG, Magnetic Resonance

Patients are administered some psychological tests, if they are positive they move on to the next stage, otherwise the patients leave the practice. If they are positive, EEG, MRI and other psychological tests are also administered.