RecruitingNCT06879730

Retrospective Evaluation of Minimally-Invasive Surgical Strategies in Ovarian Neoplasms (REMISSION Study)


Sponsor

Jvan Casarin, MD PhD

Enrollment

1,500 participants

Start Date

May 15, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study aims to evaluate the outcomes of patients with early-stage epithelial ovarian cancer who are treated with minimally invasive surgery (such as laparoscopic or robotic surgery). Specifically, the study will look at: 1. Post-Surgery Complications * What is the rate of complications within 30 days after surgery? * How often do patients require readmission to the hospital, re-operation, or conversion to open surgery? 2. Cancer Outcomes * What is the rate of cancer upstaging (when the cancer spreads to a more advanced stage during surgery for example because of an intra-operative ovarian cyst rupture)? * What are the overall survival and disease-free survival rates for patients treated with minimally invasive surgery? Researchers will compare two groups of patients: Group 1: Patients with early-stage ovarian cancer treated with minimally invasive surgery. Group 2: Patients with early-stage ovarian cancer treated with open surgery. The goal is to see if there are any differences in post-surgery complications, recovery, and cancer outcomes between the two groups. Fertility-Sparing Treatment: The study will also compare patients who are undergoing fertility-sparing treatments for early-stage ovarian cancer. Two subgroups will be looked at: * Patients receiving fertility-sparing surgery through a minimally invasive procedure. * Patients receiving fertility-sparing surgery through an open surgery. The same outcomes (complications, survival, etc.) will be assessed and compared between these two groups as well.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This retrospective study looks back at data from women who had surgery for early-stage ovarian cancer between 2014 and 2023. Researchers are comparing outcomes between patients who had traditional open surgery versus minimally invasive surgery (laparoscopic or robotic) to determine which approach is safer and more effective. **You may be eligible if:** - You had surgery for apparent early-stage ovarian cancer between January 2014 and December 2023 - Your surgery involved staging (to determine how far the cancer had spread) - You had either open, laparoscopic, or robotic-assisted surgery **You may NOT be eligible if:** - Your cancer was at an advanced stage at the time of surgery - Your surgical records are unavailable or incomplete - You had a different type of gynecologic cancer Note: Since this is a retrospective (look-back) study, participants have already had their surgery — this study reviews existing medical records rather than enrolling new patients for treatment. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Ospedale Filippo del Ponte

Varese, Varese, Italy

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NCT06879730