RecruitingNot ApplicableNCT06880016

Evaluation of Serial Lung Ultrasound Data After Surfactant Treatments Applied With Different Methods in Preterm Babies


Sponsor

Konya City Hospital

Enrollment

68 participants

Start Date

Jul 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the relationship between the method of surfactant administration and improvements in serial lung ultrasound findings in preterm infants requiring surfactant therapy.


Eligibility

Min Age: 1 DayMax Age: 5 Days

Inclusion Criteria2

  • Infants of families who agree to participate in the study
  • Preterm infants born before 32 weeks of gestation requiring surfactant therapy due to an RDS diagnosis.

Exclusion Criteria3

  • Infants whose families did not provide consent
  • Infants with a syndromic appearance or congenital heart disease
  • Preterm infants born after 32 weeks of gestation

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Interventions

DIAGNOSTIC_TESTEvaluation of serial lung ultrasound data after ENSURE surfactant treatments

Intubating the infant, administering intratracheal surfactant, and then extubating them back to nasal respiratory support (ENSURE method)

DIAGNOSTIC_TESTEvaluation of serial lung ultrasound data after LISA surfactant treatments

Delivering surfactant via a thin catheter (5F) directly into the trachea while the infant remains on existing nasal respiratory support, without disconnecting them from it (LISA method)


Locations(1)

Melek Buyukeren

Konya, Karatay, Turkey (Türkiye)

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NCT06880016


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